The potential immunomodular activity of esential oils in livestock
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Date
2019Author
Ratajac, Radomir
Petrović, Jelena
Prodanov-Radulović, Jasna
Pušić, Ivan
Žekić-Stošić, Marina
Stojanov, Igor
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The goal of this study was to examine the possibility of using herbal preparations in the
therapy of local inflammatory processes of the livestock endometrium, as alternative or
supportive therapy with conventional medicines. Quantitative determination of the phagocytic
capacity of leukocytes from cows blood samples was performed using the commercial
test PHAGOTEST®. Fluorescein labeled E. coli bacteria were used as phagocytic particles.
The test can determine the percentage of monocytes and granulocytes that performed
phagocytosis, the phagocytic ability of individual cells and their activity. The Rtanj tea extract
has been found to have a high effect in activating the respiratory burst in most of polymorphonuclear
leukocytes. At the same time, the intensity of the reaction and combustion
power of ingested bacteria, had similar values between the experimental groups and the
positive control. Based on the results of these tests, the herb tea (Satureja montana L.) was
selected as a species for pharmaceutical use and further testing to determine the dose and
route of administration for the prophylaxis and therapy of endometritis in animals.