| dc.contributor.author | Lalošević, Dušan | |
| dc.contributor.author | Stankov, Srđan | |
| dc.contributor.author | Bojat, Veselin | |
| dc.contributor.author | Lazić, Sava | |
| dc.contributor.author | Petrović, Tamaš | |
| dc.contributor.author | Vidanović, Dejan | |
| dc.contributor.author | Vujin, Dragana | |
| dc.contributor.author | Simin, Verica | |
| dc.contributor.author | Lalošević, Vesna | |
| dc.date.accessioned | 2021-07-19T08:12:28Z | |
| dc.date.available | 2021-07-19T08:12:28Z | |
| dc.date.issued | 2021 | |
| dc.identifier.issn | 1821-1585 | |
| dc.identifier.uri | https://repo.niv.ns.ac.rs/xmlui/handle/123456789/396 | |
| dc.description.abstract | Virus isolation on Vero cell culture was successful from a single and a pool of 4 swabs of
patients positive in a rapid antigen test for SARS-CoV-2. Genome RNA sequencing of
both SARS-CoV-2 isolates designed as Novi Sad 2021-1 and 2 (NS21-1; NS21-2) proved
that they belong to the „British” strain. Adaptation of virus isolates to Vero culture was
done in three consecutive passages, whereby the incubation was shortened from 6 days to
36 hours until the appearance of the first cytopathic effect (CPe). Viral harvest titers
ranged from 4 to 7 logCCID50/mL. Inactivation of the isolates was successful with betapropiolactone, 1: 1000, with preserved viral antigenicity. | en_US |
| dc.language.iso | other | en_US |
| dc.source | Medical Data : medicinska revija =medical review | sr |
| dc.subject | SARS-CoV-2 | en_US |
| dc.subject | Novi Sad | en_US |
| dc.subject | isolation | en_US |
| dc.subject | viral inactivation | en_US |
| dc.title | Novi korona-virus (SARS-cov-2) izolati Novi Sad 2021, identifikacija i inaktivacija | en_US |
| dc.title.alternative | Novel coronavirus (SARS-cov-2) isolates Novi Sad 2021, identification and inactivation | en_US |
| dc.type | Article | en_US |
