Ispitivanje osetljivosti na antibiotike meticilin rezistentnog Staphylococcus pseudintermedius (MRSP) poreklom od zdravih pasa

Abstract

Treatment of infection caused by methicillin-resistant Staphylococcus pseudintermedius (MRSP) has become a real challenge in veterinary practice because MRSP is often resistant to different classes of antibiotics. We examined 312 nasal swabs from 156 clinically healthy dogs (from both nostrils) for the presence of MRSP strains, as well as their sensitivity to other antibiotics. Antibiotic susceptibility was tested according to the guidelines of the European Committee for Antimicrobial Susceptibility Testing – EUCAST, and confirmation of methicillin resistance was done by detection of mecA gene by PCR method. Of the 312 nasal swabs, MRSP was isolated from 17 swabs (5.44%), which in addition to methicillin resistance were also resistant to fluoroquinolones, aminoglycosides, trimethoprim, sulfonamides, chloramphenicol, tetracyclines, macrolides and lincosamides. The results of our study show that clinically healthy dogs can be carriers of multidrug-resistant MRSP strains, and thus reservoirs of these zoonotic pathogens for humans.