| dc.contributor.author | Kurćubić, Vladimir | |
| dc.contributor.author | Mašković, Pavle | |
| dc.contributor.author | Petrović, Tamaš | |
| dc.contributor.author | Lazić, Sava | |
| dc.contributor.author | Đukić, Dragutin | |
| dc.contributor.author | Ilić, Zoran | |
| dc.contributor.author | Đoković, Radojica | |
| dc.contributor.author | Petrović, Miloš | |
| dc.date.accessioned | 2019-10-30T10:59:27Z | |
| dc.date.available | 2019-10-30T10:59:27Z | |
| dc.date.issued | 2019-07 | |
| dc.identifier.isbn | 978-86-6042-008-6 | |
| dc.identifier.uri | https://repo.niv.ns.ac.rs/xmlui/handle/123456789/62 | |
| dc.description.abstract | In this study, we investigated the in vitro antiviral activity of five
selected plant extracts against Bovine Herpes Virus-1 (BHV-1) subtype 1.1
and Bovine Viral Diarrhoea Virus (BVDV) genotype 1, which with other
viral and bacterial agents cause Bovine Respiratory Disease Complex
(BRDC). Ethanol (alcohol) and aqueous extracts were prepared for all five
plant species studied. Two prepared samples of aqueous plant
extracts/macerates had antiviral effect against BHV-1 as a representative of
herpesvirus (DNA virus), but none of the samples showed an antiviral effect
against BVDV genotype 1, a NADL strain, that belongs to RNA viruses. In
our study, Selectivity Index (SI = CTC50/EC50) for aqueous extracts of
Matricaria chamomilla (SI = 32) and Achillea millefolium (SI = ≥ 8)
indicates a significant selective inhibition of DNA virus (BHV-1, strain
TN41). On the basis of the obtained results, future research is needed, which
would reveal the active ingredients of the investigated plants and
mechanisms of their antiviral effect. | en_US |
| dc.description.sponsorship | This study is a part of the technological development project Ref. No.
31001, financially supported by the Ministry of Education, Science and
Technological development of the Republic of Serbia. The authors would
like to thank Boţica Šulibrk for technical assistance in laboratory
experiments. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Balkans Scientific Center of the Russian Academy of Natural Sciences, Belgrade | en_US |
| dc.source | 1st International Symposium Modern Trends in Agricurtural Production and Environmental Protection, July 02-05, 2019, Tivat, Montenegro | en |
| dc.subject | antiviral activity | en_US |
| dc.subject | BHV-1 | en_US |
| dc.subject | BVDV genotype 1 | en_US |
| dc.subject | indigenous plants | en_US |
| dc.title | Antiviral activity in vitro of five selected indigenous plants against bovine herpes virus-1 (BHV-1) and bovine viral diarrhoea virus (BVDV) | en_US |
| dc.title.alternative | | en_US |
| dc.type | Book chapter | en_US |
